5N2W

WT-Parkin and pUB complex

Summary for 5N2W

DescriptorE3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ZINC ION, ... (6 entities in total)
Functional Keywordscomplex structure of parkin and pub, transferase, ligase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm, cytosol  O60260
Ubiquitin: Cytoplasm  P0CG47
Total number of polymer chains2
Total molecular weight54949.82
Authors
Kumar, A.,Chaugule, V.K.,Johnson, C.,Toth, R.,Sundaramoorthy, R.,Knebel, A.,Walden, H. (deposition date: 2017-02-08, release date: 2017-04-19, Last modification date: 2018-01-31)
Primary citation
Kumar, A.,Chaugule, V.K.,Condos, T.E.C.,Barber, K.R.,Johnson, C.,Toth, R.,Sundaramoorthy, R.,Knebel, A.,Shaw, G.S.,Walden, H.
Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24:475-483, 2017
PubMed: 28414322 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb.3400
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.68 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25450.7%5.5%4.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5n2w
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Molmil generated image of 5n2w
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