5MZO

UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum (open conformation)

5MZO の概要

• エントリーDOI: 10.2210/pdb5mzo/pdb
• 分子名称: UDP-glucose-glycoprotein glucosyltransferase-like protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: glycoprotein, misfolding, transferase, endoplasmic reticulum
• 由来する生物種: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 172207.78

構造登録者

Roversi, P.,Caputo, A.T.,Hill, J.,Alonzi, D.S.,Zitzmann, N. (登録日: 2017-02-01, 公開日: 2017-07-26, 最終更新日: 2024-01-17)

• 主引用文献: Roversi, P.,Marti, L.,Caputo, A.T.,Alonzi, D.S.,Hill, J.C.,Dent, K.C.,Kumar, A.,Levasseur, M.D.,Lia, A.,Waksman, T.,Basu, S.,Soto Albrecht, Y.,Qian, K.,McIvor, J.P.,Lipp, C.B.,Siliqi, D.,Vasiljevic, S.,Mohammed, S.,Lukacik, P.,Walsh, M.A.,Santino, A.,Zitzmann, N.; Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint.; Proc. Natl. Acad. Sci. U.S.A., 114:8544-8549, 2017; PubMed: 28739903; DOI: 10.1073/pnas.1703682114

実験手法

X-RAY DIFFRACTION (3.48 Å)