5MZM

Structure of H-2Db in complex with TEIPP APL Trh4 p3P

5MZM の概要

• エントリーDOI: 10.2210/pdb5mzm/pdb
• 分子名称: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, Ceramide synthase 5 derived peptide Trh4 p3P, ... (6 entities in total)
• 機能のキーワード: cancer, neo-epitope, t-cell epitopes associated with impaired peptide processing, mhc-i, immune system
• 由来する生物種: Mus musculus (Mouse); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 89949.08

構造登録者

Hafstrand, I.,Achour, A.,Sandalova, T. (登録日: 2017-02-01, 公開日: 2018-03-21, 最終更新日: 2024-01-17)

• 主引用文献: Hafstrand, I.,Doorduijn, E.M.,Sun, R.,Talyzina, A.,Sluijter, M.,Pellegrino, S.,Sandalova, T.,Duru, A.D.,van Hall, T.,Achour, A.; The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability.; J. Immunol., 200:2860-2868, 2018; PubMed: 29507106; DOI: 10.4049/jimmunol.1700228

実験手法

X-RAY DIFFRACTION (2.4 Å)