5MOX
OXA-10 Avibactam complex with bound CO2
Summary for 5MOX
Entry DOI | 10.2210/pdb5mox/pdb |
Descriptor | Beta-lactamase OXA-10, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, SODIUM ION, ... (6 entities in total) |
Functional Keywords | antibiotic resistance, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 56211.77 |
Authors | Brem, J. (deposition date: 2016-12-14, release date: 2017-07-12, Last modification date: 2024-01-17) |
Primary citation | Lohans, C.T.,Wang, D.Y.,Jorgensen, C.,Cahill, S.T.,Clifton, I.J.,McDonough, M.A.,Oswin, H.P.,Spencer, J.,Domene, C.,Claridge, T.D.W.,Brem, J.,Schofield, C.J. (13)C-Carbamylation as a mechanistic probe for the inhibition of class D beta-lactamases by avibactam and halide ions. Org. Biomol. Chem., 15:6024-6032, 2017 Cited by PubMed: 28678295DOI: 10.1039/c7ob01514c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.41 Å) |
Structure validation
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