5MMZ

Structure of PRL-1 in complex with the Bateman domain of CNNM2

Summary for 5MMZ

• Entry DOI: 10.2210/pdb5mmz/pdb
• Related: 5LXQ
• Descriptor: Metal transporter CNNM2, Protein tyrosine phosphatase type IVA 1 (3 entities in total)
• Functional Keywords: cyclin m, magnesium transport, acdp, metal transport
• Biological source: Mus musculus (Mouse); More
• Cellular location: Cell membrane ; Multi-pass membrane protein : Q3TWN3; Cell membrane : Q63739
• Total number of polymer chains: 2
• Total formula weight: 37711.50

Authors

Gimenez-Mascarell, P.,Oyenarte, I.,Hardy, S.,Breiderhoff, T.,Stuiver, M.,Kostantin, E.,Diercks, T.,Pey, A.L.,Ereno-Orbea, J.,Martinez-Chantar, M.L.,Khalaf-Nazzal, R.,Claverie-Martin, F.,Muller, D.,Tremblay, M.L.,Martinez-Cruz, L.A. (deposition date: 2016-12-12, release date: 2016-12-21, Last modification date: 2024-01-17)

• Primary citation: Gimenez-Mascarell, P.,Oyenarte, I.,Hardy, S.,Breiderhoff, T.,Stuiver, M.,Kostantin, E.,Diercks, T.,Pey, A.L.,Ereno-Orbea, J.,Martinez-Chantar, M.L.,Khalaf-Nazzal, R.,Claverie-Martin, F.,Muller, D.,Tremblay, M.L.,Martinez-Cruz, L.A.; Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.; J. Biol. Chem., 292:786-801, 2017; PubMed: 27899452; DOI: 10.1074/jbc.M116.759944

Experimental method

X-RAY DIFFRACTION (2.4 Å)