5MKG

PA3825-EAL Ca-CdG Structure

Summary for 5MKG

Entry DOI	10.2210/pdb5mkg/pdb
Descriptor	Diguanylate phosphodiesterase, CALCIUM ION, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ... (5 entities in total)
Functional Keywords	eal, phosphodiesterase, biofilm formation, p aeruginosa, pa3825, hydrolase
Biological source	Pseudomonas aeruginosa More
Total number of polymer chains	2
Total formula weight	58283.02
Authors	Horrell, S.,Bellini, D.,Strange, R.,Wagner, A.,Walsh, M. (deposition date: 2016-12-04, release date: 2016-12-14, Last modification date: 2023-03-22)
Primary citation	Bellini, D.,Horrell, S.,Hutchin, A.,Phippen, C.W.,Strange, R.W.,Cai, Y.,Wagner, A.,Webb, J.S.,Tews, I.,Walsh, M.A. Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases. Sci Rep, 7:42166-42166, 2017 Cited by PubMed: 28186120 DOI: 10.1038/srep42166 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.44 Å)

Structure validation