5MGG
Crystal Structure of BAZ2B bromodomain in complex with 4-chloropyridine derivative 3
Summary for 5MGG
Entry DOI | 10.2210/pdb5mgg/pdb |
Related | 5MGE 5MGF |
Descriptor | Bromodomain adjacent to zinc finger domain protein 2B, 4-chloranyl-~{N}-methyl-pyridine-2-carboxamide (3 entities in total) |
Functional Keywords | four helical bundle, transcription |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q9UIF8 |
Total number of polymer chains | 1 |
Total formula weight | 13702.17 |
Authors | Lolli, G.,Spiliotopoulos, D.,Caflisch, A. (deposition date: 2016-11-21, release date: 2017-04-12, Last modification date: 2024-01-17) |
Primary citation | Spiliotopoulos, D.,Wamhoff, E.C.,Lolli, G.,Rademacher, C.,Caflisch, A. Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139:564-572, 2017 Cited by PubMed: 28837921DOI: 10.1016/j.ejmech.2017.08.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report