5MC4
Crystal Structure of Gly448Arg mutant of Human Prolidase with Mn ions and GlyPro ligand
Summary for 5MC4
Entry DOI | 10.2210/pdb5mc4/pdb |
Related | 5M4J 5MBY 5MBZ 5MC0 5MC1 5MC2 5MC3 5MC5 |
Descriptor | Xaa-Pro dipeptidase, MANGANESE (II) ION, HYDROXIDE ION, ... (7 entities in total) |
Functional Keywords | prolidase, peptidase, hydrolysis, pita-bread, metalloenzyme, mutation, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 108128.25 |
Authors | Wilk, P.,Mueller, U.,Dobbek, H.,Weiss, M.S. (deposition date: 2016-11-09, release date: 2017-12-20, Last modification date: 2024-01-17) |
Primary citation | Wilk, P.,Uehlein, M.,Piwowarczyk, R.,Dobbek, H.,Mueller, U.,Weiss, M.S. Structural basis for prolidase deficiency disease mechanisms. FEBS J., 285:3422-3441, 2018 Cited by PubMed: 30066404DOI: 10.1111/febs.14620 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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