5MAY

STRUCTURE OF THE LECB LECTIN FROM PSEUDOMONAS AERUGINOSA STRAIN PA14 IN COMPLEX WITH 2-Thiophenesulfonamide-N-(beta-L-fucopyranosyl methyl)

Summary for 5MAY

Entry DOI	10.2210/pdb5may/pdb
Related	5a6q
Descriptor	Fucose-binding lectin PA-IIL, CALCIUM ION, beta-L-fucopyranose, ... (5 entities in total)
Functional Keywords	sugar binding protein, lectin, lecb, pseudomonas aeruginosa pa14, glycoinhibitors
Biological source	Pseudomonas aeruginosa (strain UCBPP-PA14)
Total number of polymer chains	4
Total formula weight	48393.07
Authors	Sommer, R.,Imberty, A.,Titz, A.,Varrot, A. (deposition date: 2016-11-07, release date: 2017-12-20, Last modification date: 2024-01-17)
Primary citation	Sommer, R.,Wagner, S.,Rox, K.,Varrot, A.,Hauck, D.,Wamhoff, E.C.,Schreiber, J.,Ryckmans, T.,Brunner, T.,Rademacher, C.,Hartmann, R.W.,Bronstrup, M.,Imberty, A.,Titz, A. Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa. J. Am. Chem. Soc., 140:2537-2545, 2018 Cited by PubMed: 29272578 DOI: 10.1021/jacs.7b11133 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation