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5M8N

Crystal structure of human tyrosinase related protein 1 in complex with mimosine

Summary for 5M8N
Entry DOI10.2210/pdb5m8n/pdb
Descriptor5,6-dihydroxyindole-2-carboxylic acid oxidase, ZINC ION, MIMOSINE, ... (12 entities in total)
Functional Keywordshuman tyrosinase related protein 1, melanin biosynthesis, tyrosinase, oxidoreductase, unknown function
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight213214.14
Authors
Lai, X.,Soler-Lopez, M.,Wichers, H.J.,Dijkstra, B.W. (deposition date: 2016-10-29, release date: 2017-07-12, Last modification date: 2020-07-29)
Primary citationLai, X.,Wichers, H.J.,Soler-Lopez, M.,Dijkstra, B.W.
Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis.
Angew. Chem. Int. Ed. Engl., 56:9812-9815, 2017
Cited by
PubMed: 28661582
DOI: 10.1002/anie.201704616
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

221051

數據於2024-06-12公開中

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