5M3V

BEAT Fc

5M3V の概要

• エントリーDOI: 10.2210/pdb5m3v/pdb
• 分子名称: Ig gamma-1 chain C region,Ig gamma-3 chain C region, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: antibody tcr bispecific interface, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Secreted : P01860 P01857
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55255.83

構造登録者

Skegro, D.,Stutz, C.,Bourquin, F.,Blein, S. (登録日: 2016-10-17, 公開日: 2017-05-10, 最終更新日: 2024-01-17)

• 主引用文献: Skegro, D.,Stutz, C.,Ollier, R.,Svensson, E.,Wassmann, P.,Bourquin, F.,Monney, T.,Gn, S.,Blein, S.; Immunoglobulin domain interface exchange as a platform technology for the generation of Fc heterodimers and bispecific antibodies.; J. Biol. Chem., 292:9745-9759, 2017; PubMed: 28450393; DOI: 10.1074/jbc.M117.782433

実験手法

X-RAY DIFFRACTION (1.97 Å)