5M2L

Structure of DNA tetrameric AGCGA-quadruplex adopted by 15-mer d(GCGAGGGAGCGAGGG), VK34, oligonucleotide found in regulatory region of the PLEKHG3 human gene

Summary for 5M2L

• Entry DOI: 10.2210/pdb5m2l/pdb
• NMR Information: BMRB: 34054
• Descriptor: DNA (5'-D(*GP*CP*GP*AP*GP*GP*GP*AP*GP*CP*GP*AP*GP*GP*G)-3') (1 entity in total)
• Functional Keywords: agcga-quadruplex, tetramer, agcga-quadruplex family, gaga-quartet, g-g n1-carbonyl symmetric base pair, plekhg3 gene, dna
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 19060.34

Authors

Kocman, V.,Plavec, J. (deposition date: 2016-10-13, release date: 2017-05-31, Last modification date: 2019-10-30)

• Primary citation: Kocman, V.,Plavec, J.; Tetrahelical structural family adopted by AGCGA-rich regulatory DNA regions.; Nat Commun, 8:15355-15355, 2017; PubMed: 28513602; DOI: 10.1038/ncomms15355

Experimental method

SOLUTION NMR