5M19

Crystal structure of PBP2a from MRSA in the presence of Oxacillin ligand

Summary for 5M19

Entry DOI	10.2210/pdb5m19/pdb
Descriptor	Penicillin-binding protein 2, CADMIUM ION, beta-muramic acid, ... (4 entities in total)
Functional Keywords	penicillin binding protein, staphylococcus aureus
Biological source	Staphylococcus aureus
Total number of polymer chains	2
Total formula weight	147750.25
Authors	Molina, R.,Batuecas, M.T.,Hermoso, J.A. (deposition date: 2016-10-07, release date: 2017-02-08, Last modification date: 2024-01-17)
Primary citation	Mahasenan, K.V.,Molina, R.,Bouley, R.,Batuecas, M.T.,Fisher, J.F.,Hermoso, J.A.,Chang, M.,Mobashery, S. Conformational Dynamics in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus, Allosteric Communication Network and Enablement of Catalysis. J. Am. Chem. Soc., 139:2102-2110, 2017 Cited by PubMed: 28099001 DOI: 10.1021/jacs.6b12565 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation