5M0R

Cryo-EM reconstruction of the maedi-visna virus (MVV) strand transfer complex

5M0R の概要

• エントリーDOI: 10.2210/pdb5m0r/pdb
• EMDBエントリー: 4139
• 分子名称: integrase, vDNA, non-transfered strand, vDNA-tDNA, transferred strand, joined to a model tDNA, ... (4 entities in total)
• 機能のキーワード: retrovirus, lentivirus, integrase, dna-binding, zn-binding, rnaseh fold, hydrolase
• 由来する生物種: Maedi visna virus (strain KV1772) (MVV); 詳細
• タンパク質・核酸の鎖数: 22
• 化学式量合計: 575736.43

構造登録者

Pye, V.E.,Ballandras-Colas, A.,Maskell, D.,Locke, J.,Kotecha, A.,Costa, A.,Cherepanov, P. (登録日: 2016-10-05, 公開日: 2017-01-18, 最終更新日: 2024-05-15)

• 主引用文献: Ballandras-Colas, A.,Maskell, D.P.,Serrao, E.,Locke, J.,Swuec, P.,Jonsson, S.R.,Kotecha, A.,Cook, N.J.,Pye, V.E.,Taylor, I.A.,Andresdottir, V.,Engelman, A.N.,Costa, A.,Cherepanov, P.; A supramolecular assembly mediates lentiviral DNA integration.; Science, 355:93-95, 2017; PubMed: 28059770; DOI: 10.1126/science.aah7002

実験手法

ELECTRON MICROSCOPY (8.2 Å)