5LRN

Structure of mono-zinc MCR-1 in P21 space group

5LRN の概要

• エントリーDOI: 10.2210/pdb5lrn/pdb
• 分子名称: Phosphatidylethanolamine transferase Mcr-1, ZINC ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: phosphotehanolamine, metalloenzyme, colistin, antibiotic resistance, transferase
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cell inner membrane ; Multi-pass membrane protein : A0A0R6L508
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72948.07

構造登録者

Hinchliffe, P.,Paterson, N.G.,Spencer, J. (登録日: 2016-08-19, 公開日: 2016-12-07, 最終更新日: 2024-01-17)

• 主引用文献: Hinchliffe, P.,Yang, Q.E.,Portal, E.,Young, T.,Li, H.,Tooke, C.L.,Carvalho, M.J.,Paterson, N.G.,Brem, J.,Niumsup, P.R.,Tansawai, U.,Lei, L.,Li, M.,Shen, Z.,Wang, Y.,Schofield, C.J.,Mulholland, A.J.,Shen, J.,Fey, N.,Walsh, T.R.,Spencer, J.; Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1.; Sci Rep, 7:39392-39392, 2017; PubMed: 28059088; DOI: 10.1038/srep39392

実験手法

X-RAY DIFFRACTION (1.55 Å)