5LQC

Crystal Structure of COMT in complex with N-[(E)-3-[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]oxolan-2-yl]prop-2-enyl]-5-(4-fluorophenyl)-2,3-dihydroxybenzamide

Summary for 5LQC

• Entry DOI: 10.2210/pdb5lqc/pdb
• Descriptor: Catechol O-methyltransferase, N-[(E)-3-[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-methylaminopurin-9-yl)oxolan-2-yl]prop-2-enyl]-5-(4-fluorophenyl)-2,3-dihydroxy-benzamide, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: methyltransferase, neurotransmitter degradation, transferase
• Biological source: Rattus norvegicus (Rat)
• Cellular location: Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734
• Total number of polymer chains: 1
• Total formula weight: 25333.22

Authors

Ehler, A.,Ellermann, M.,Lerner, C.,Rudolph, M.G. (deposition date: 2016-08-16, release date: 2016-08-31, Last modification date: 2024-05-01)

• Primary citation: Ellermann, M.,Lerner, C.,Rudolph, M.G.; no title yet; To be published,

Experimental method

X-RAY DIFFRACTION (1.903 Å)