5LQC
Crystal Structure of COMT in complex with N-[(E)-3-[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]oxolan-2-yl]prop-2-enyl]-5-(4-fluorophenyl)-2,3-dihydroxybenzamide
Summary for 5LQC
Entry DOI | 10.2210/pdb5lqc/pdb |
Descriptor | Catechol O-methyltransferase, N-[(E)-3-[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-methylaminopurin-9-yl)oxolan-2-yl]prop-2-enyl]-5-(4-fluorophenyl)-2,3-dihydroxy-benzamide, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | methyltransferase, neurotransmitter degradation, transferase |
Biological source | Rattus norvegicus (Rat) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734 |
Total number of polymer chains | 1 |
Total formula weight | 25333.22 |
Authors | Ehler, A.,Ellermann, M.,Lerner, C.,Rudolph, M.G. (deposition date: 2016-08-16, release date: 2016-08-31, Last modification date: 2024-05-01) |
Primary citation | Ellermann, M.,Lerner, C.,Rudolph, M.G. no title yet To be published, |
Experimental method | X-RAY DIFFRACTION (1.903 Å) |
Structure validation
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