5LLG
Crystal structure of human carbonic anhydrase isozyme II with 4-Propylthiobenzenesulfonamide
Summary for 5LLG
Entry DOI | 10.2210/pdb5llg/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, 4-(propylsulfanyl)benzenesulfonamide, ... (6 entities in total) |
Functional Keywords | drug design, carbonic anhydrase, benzenesulfonamide, metal-binding, lyase-lyase inhibitor complex, lyase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 30136.58 |
Authors | Smirnov, A.,Manakova, E.,Grazulis, S. (deposition date: 2016-07-27, release date: 2017-08-16, Last modification date: 2024-01-10) |
Primary citation | Smirnov, A.,Zubriene, A.,Manakova, E.,Grazulis, S.,Matulis, D. Crystal structure correlations with the intrinsic thermodynamics of human carbonic anhydrase inhibitor binding. PeerJ, 6:e4412-e4412, 2018 Cited by PubMed: 29503769DOI: 10.7717/peerj.4412 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.12 Å) |
Structure validation
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