5LIE

Crystal structure of Mycobacterium tuberculosis CYP126A1 in complex with imidazole

5LIE の概要

• エントリーDOI: 10.2210/pdb5lie/pdb
• 分子名称: Putative cytochrome P450 126, PROTOPORPHYRIN IX CONTAINING FE, IMIDAZOLE, ... (4 entities in total)
• 機能のキーワード: monoxygenase, cytochrome p450, oxidoreductase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 93323.84

構造登録者

Levy, C.,Munro, A.W.,Leys, D. (登録日: 2016-07-14, 公開日: 2016-12-21, 最終更新日: 2024-01-10)

• 主引用文献: Chenge, J.T.,Duyet, L.V.,Swami, S.,McLean, K.J.,Kavanagh, M.E.,Coyne, A.G.,Rigby, S.E.,Cheesman, M.R.,Girvan, H.M.,Levy, C.W.,Rupp, B.,von Kries, J.P.,Abell, C.,Leys, D.,Munro, A.W.; Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1.; J. Biol. Chem., 292:1310-1329, 2017; PubMed: 27932461; DOI: 10.1074/jbc.M116.748822

実験手法

X-RAY DIFFRACTION (1.799 Å)