5LE8

Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_15_D12

Summary for 5LE8

• Entry DOI: 10.2210/pdb5le8/pdb
• Descriptor: DD_D12_15_D12, SULFATE ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: de novo protein, designed ankyrin repeat proteins; protein design; protein engineering; rigid domain fusions
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 73083.36

Authors

Batyuk, A.,Wu, Y.,Mittl, P.R.,Plueckthun, A. (deposition date: 2016-06-29, release date: 2017-08-02, Last modification date: 2024-01-10)

• Primary citation: Wu, Y.,Batyuk, A.,Honegger, A.,Brandl, F.,Mittl, P.R.E.,Pluckthun, A.; Rigidly connected multispecific artificial binders with adjustable geometries.; Sci Rep, 7:11217-11217, 2017; PubMed: 28894181; DOI: 10.1038/s41598-017-11472-x

Experimental method

X-RAY DIFFRACTION (1.78 Å)