5LC8

Crystal Structure of specific mutant from Pseudomonas aeruginosa Lipoxygenase at 1.8A resolution

5LC8 の概要

• エントリーDOI: 10.2210/pdb5lc8/pdb
• 分子名称: Arachidonate 15-lipoxygenase, FE (II) ION, GLYCEROL, ... (7 entities in total)
• 機能のキーワード: non-heme iron enzyme, protein-phospholipid complex, oxidoreductase, a420g mutant, eicosanoids, infectious diseases, arachidonate 15s-lipoxygenase, linoleate 13s-lipoxygenase
• 由来する生物種: Pseudomonas aeruginosa
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 73809.29

構造登録者

Kalms, J.,Banthiya, S.,Galemou Yoga, E.,Kuhn, H.,Scheerer, P. (登録日: 2016-06-20, 公開日: 2017-01-25, 最終更新日: 2024-01-10)

• 主引用文献: Kalms, J.,Banthiya, S.,Galemou Yoga, E.,Hamberg, M.,Holzhutter, H.G.,Kuhn, H.,Scheerer, P.; The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity.; Biochim. Biophys. Acta, 1862:463-473, 2017; PubMed: 28093240; DOI: 10.1016/j.bbalip.2017.01.003

実験手法

X-RAY DIFFRACTION (1.8 Å)