5LAU

Oceanobacillus iheyensis macrodomain mutant G37V with ADPR

Summary for 5LAU

Entry DOI	10.2210/pdb5lau/pdb
Descriptor	MacroD-type macrodomain, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, GLYCEROL, ... (4 entities in total)
Functional Keywords	macrodomain, adp-ribosylation, deacetylase, hydrolase
Biological source	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Total number of polymer chains	1
Total formula weight	23581.48
Authors	Gil-Ortiz, F.,Zapata-Perez, R.,Martinez, A.B.,Juanhuix, J.,Sanchez-Ferrer, A. (deposition date: 2016-06-15, release date: 2017-05-03, Last modification date: 2024-01-10)
Primary citation	Zapata-Perez, R.,Gil-Ortiz, F.,Martinez-Monino, A.B.,Garcia-Saura, A.G.,Juanhuix, J.,Sanchez-Ferrer, A. Structural and functional analysis of Oceanobacillus iheyensis macrodomain reveals a network of waters involved in substrate binding and catalysis. Open Biol, 7:-, 2017 Cited by PubMed: 28446708 DOI: 10.1098/rsob.160327 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation