5L6I
Uba1 in complex with Ub-MLN4924 covalent adduct
Summary for 5L6I
Entry DOI | 10.2210/pdb5l6i/pdb |
Descriptor | Ubiquitin-activating enzyme E1 1, Ubiquitin-40S ribosomal protein S31, SULFATE ION, ... (7 entities in total) |
Functional Keywords | e1 enzyme, ubiquitin activation, uba1 inhibitor, adenosyl sulfamate, ligase |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Total number of polymer chains | 5 |
Total formula weight | 257645.91 |
Authors | Misra, M.,Schindelin, H. (deposition date: 2016-05-30, release date: 2017-06-14, Last modification date: 2024-01-10) |
Primary citation | Misra, M.,Kuhn, M.,Lobel, M.,An, H.,Statsyuk, A.V.,Sotriffer, C.,Schindelin, H. Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme. Structure, 25:1120-1129.e3, 2017 Cited by PubMed: 28578874DOI: 10.1016/j.str.2017.05.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.76 Å) |
Structure validation
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