5L6I

Uba1 in complex with Ub-MLN4924 covalent adduct

Summary for 5L6I

• Entry DOI: 10.2210/pdb5l6i/pdb
• Descriptor: Ubiquitin-activating enzyme E1 1, Ubiquitin-40S ribosomal protein S31, SULFATE ION, ... (7 entities in total)
• Functional Keywords: e1 enzyme, ubiquitin activation, uba1 inhibitor, adenosyl sulfamate, ligase
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 5
• Total formula weight: 257645.91

Authors

Misra, M.,Schindelin, H. (deposition date: 2016-05-30, release date: 2017-06-14, Last modification date: 2024-01-10)

• Primary citation: Misra, M.,Kuhn, M.,Lobel, M.,An, H.,Statsyuk, A.V.,Sotriffer, C.,Schindelin, H.; Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme.; Structure, 25:1120-1129.e3, 2017; PubMed: 28578874; DOI: 10.1016/j.str.2017.05.001

Experimental method

X-RAY DIFFRACTION (2.76 Å)