5L6H

Uba1 in complex with Ub-ABPA3 covalent adduct

Replaces:  3CMM
Replaces:  4NNJ

Summary for 5L6H

DescriptorUbiquitin-activating enzyme E1 1, Ubiquitin-40S ribosomal protein S31, SULFATE ION, ... (9 entities in total)
Functional Keywordse1 enzyme, ubiquitin activation, uba1 inhibitor, adenosyl sulfamate, ligase
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
More
Cellular locationCytoplasm P22515
Ubiquitin: Cytoplasm . 40S ribosomal protein S31: Cytoplasm  P05759
Total number of polymer chains5
Total molecular weight256991
Authors
Misra, M.,Schindelin, H. (deposition date: 2016-05-30, release date: 2017-06-14, Last modification date: 2017-09-06)
Primary citation
Misra, M.,Kuhn, M.,Lobel, M.,An, H.,Statsyuk, A.V.,Sotriffer, C.,Schindelin, H.
Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme.
Structure, 25:1120-1129.e3, 2017
PubMed: 28578874 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2017.05.001
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21930.2%5.3%7.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5l6h
no rotation
Molmil generated image of 5l6h
rotated about x axis by 90°
Molmil generated image of 5l6h
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 5l6h
no rotation
Molmil generated image of 5l6h
rotated about x axis by 90°
Molmil generated image of 5l6h
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (5l6h.pdb2.gz [400.52 KB])
Coordinate files for Biological unit (5l6h.pdb1.gz [377.55 KB])