5L4W

Crystal structure of FimH lectin domain in complex with 3-Fluoro-Heptylmannoside

Summary for 5L4W

• Entry DOI: 10.2210/pdb5l4w/pdb
• Descriptor: Protein FimH, heptyl 3-fluoro-alpha-D-mannopyranoside (3 entities in total)
• Functional Keywords: fimh, type 1 pilus, urinary tract infection, uti, carbohydrate, lectin, mannose, cell adhesion, sugar binding protein
• Biological source: Escherichia coli (strain K12)
• Cellular location: Fimbrium : P08191
• Total number of polymer chains: 3
• Total formula weight: 51591.48

Authors

Jakob, R.P.,Zihlmann, P.,Rabbani, S.,Maier, T.,Ernst, B. (deposition date: 2016-05-26, release date: 2017-06-21, Last modification date: 2024-01-10)

• Primary citation: Zihlmann, P.,Jiang, X.,Sager, C.P.,Fiege, B.,Jakob, R.P.,Siegrist, S.,Zalewski, A.,Rabbani, S.,Eris, D.,Silbermann, M.,Pang, L.,Muhlethaler, T.,Sharpe, T.,Maier, T.,Ernst, B.; High-Affinity Carbohydrate-Lectin Interactions: How Nature Makes it Possible; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)