5KUB

Bacillus cereus DNA glycosylase AlkD bound to 7-methylguanine nucleobase and DNA containing an oxocarbenium-intermediate analog

5KUB の概要

• エントリーDOI: 10.2210/pdb5kub/pdb
• 分子名称: DNA-7-methylguanine glycosylase, DNA (5'-D(*CP*CP*CP*GP*AP*(NRI)P*AP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*AP*CP*TP*CP*TP*CP*GP*GP*G)-3'), ... (5 entities in total)
• 機能のキーワード: dna glycosylase, protein-dna complex, heat-like repeat, hydrolase-dna complex, hydrolase/dna
• 由来する生物種: Bacillus cereus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 35920.87

構造登録者

Mullins, E.A.,Eichman, B.F. (登録日: 2016-07-13, 公開日: 2016-09-14, 最終更新日: 2023-10-04)

• 主引用文献: Parsons, Z.D.,Bland, J.M.,Mullins, E.A.,Eichman, B.F.; A Catalytic Role for C-H/ pi Interactions in Base Excision Repair by Bacillus cereus DNA Glycosylase AlkD.; J.Am.Chem.Soc., 138:11485-11488, 2016; PubMed: 27571247; DOI: 10.1021/jacs.6b07399

実験手法

X-RAY DIFFRACTION (1.73 Å)