5KOF

Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and Acyl Carrier Protein, AcpP

Summary for 5KOF

Entry DOI	10.2210/pdb5kof/pdb
Descriptor	3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-[2-(prop-2-enoylamino)ethylamino]propyl]amino]butyl] dihydrogen phosphate, ... (4 entities in total)
Functional Keywords	crosslinked, ketosynthase, acp, complex, transferase
Biological source	Escherichia coli More
Total number of polymer chains	4
Total formula weight	103536.17
Authors	Milligan, J.C.,Jackson, D.R.,Barajas, J.F.,Tsai, S.C. (deposition date: 2016-06-30, release date: 2018-01-24, Last modification date: 2023-10-04)
Primary citation	Milligan, J.C.,Lee, D.J.,Jackson, D.R.,Schaub, A.J.,Beld, J.,Barajas, J.F.,Hale, J.J.,Luo, R.,Burkart, M.D.,Tsai, S.C. Molecular basis for interactions between an acyl carrier protein and a ketosynthase. Nat.Chem.Biol., 15:669-671, 2019 Cited by PubMed: 31209348 DOI: 10.1038/s41589-019-0301-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation