5KK4

Crystal Structure of the Plant Defensin NsD7 bound to Phosphatidic Acid

Summary for 5KK4

Entry DOI	10.2210/pdb5kk4/pdb
Descriptor	NsD7, 1,2-ETHANEDIOL, SULFATE ION, ... (6 entities in total)
Functional Keywords	defensin, phospholipid, oligomer, phosphatidic acid, antimicrobial protein
Biological source	Nicotiana suaveolens x Nicotiana tabacum
Total number of polymer chains	6
Total formula weight	36746.49
Authors	Kvansakul, M.,Hulett, M.D.,Lay, F.T. (deposition date: 2016-06-21, release date: 2016-10-05, Last modification date: 2023-09-27)
Primary citation	Kvansakul, M.,Lay, F.T.,Adda, C.G.,Veneer, P.K.,Baxter, A.A.,Phan, T.K.,Poon, I.K.,Hulett, M.D. Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization. Proc.Natl.Acad.Sci.USA, 113:11202-11207, 2016 Cited by PubMed: 27647905 DOI: 10.1073/pnas.1607855113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation