5KDM

Crystal structure of EBV tegument protein BNRF1 in complex with histone chaperone DAXX and histones H3.3-H4

5KDM の概要

• エントリーDOI: 10.2210/pdb5kdm/pdb
• 分子名称: Histone H3.3, Histone H4, Death domain-associated protein 6, ... (4 entities in total)
• 機能のキーワード: histone chaperone, gene repression, chaperone - dna binding protein complex, chaperone / dna binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Nucleus: P84243 P62805; Cytoplasm . Isoform beta: Nucleus . Isoform gamma: Nucleus : Q9UER7; Virion tegument : Q1HVJ0
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 74632.84

構造登録者

Huang, H.,Patel, D. (登録日: 2016-06-08, 公開日: 2016-09-07, 最終更新日: 2023-09-27)

• 主引用文献: Huang, H.,Deng, Z.,Vladimirova, O.,Wiedmer, A.,Lu, F.,Lieberman, P.M.,Patel, D.J.; Structural basis underlying viral hijacking of a histone chaperone complex.; Nat Commun, 7:12707-12707, 2016; PubMed: 27581705; DOI: 10.1038/ncomms12707

実験手法

X-RAY DIFFRACTION (3.5 Å)