5K8S
cAMP bound PfPKA-R (297-441)
Summary for 5K8S
Entry DOI | 10.2210/pdb5k8s/pdb |
Related | 5KBF |
Descriptor | CAMP-dependent protein kinase regulatory subunit, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total) |
Functional Keywords | plasmodium falciparum, pka, protein kinase a, camp, cbd, cyclic nucleotide binding, cnb, regulatory domain, r, transferase |
Biological source | Plasmodium falciparum (isolate 3D7) |
Total number of polymer chains | 2 |
Total formula weight | 34385.17 |
Authors | Littler, D.R.,Gilson, P.R.,Crabb, B.S.,Rossjohn, J.J. (deposition date: 2016-05-31, release date: 2016-10-12, Last modification date: 2023-09-27) |
Primary citation | Littler, D.R.,Bullen, H.E.,Harvey, K.L.,Beddoe, T.,Crabb, B.S.,Rossjohn, J.,Gilson, P.R. Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit. J. Biol. Chem., 291:25375-25386, 2016 Cited by PubMed: 27738107DOI: 10.1074/jbc.M116.750174 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.15 Å) |
Structure validation
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