5K7W
Crystal structure of the catalytic domain of Mettl3/Mettl14 complex with SAH
Summary for 5K7W
| Entry DOI | 10.2210/pdb5k7w/pdb |
| Related | 5K7M 5K7U |
| Descriptor | N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total) |
| Functional Keywords | methyltransferase, methyladenosine, m6a, transferase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 65690.61 |
| Authors | Wang, P.,Doxtader, K.A.,Nam, Y. (deposition date: 2016-05-26, release date: 2016-07-06, Last modification date: 2024-02-28) |
| Primary citation | Wang, P.,Doxtader, K.A.,Nam, Y. Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases. Mol.Cell, 63:306-317, 2016 Cited by PubMed: 27373337DOI: 10.1016/j.molcel.2016.05.041 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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