5K6A

Trypanosoma brucei Pteridine reductase 1 (PTR1) in complex with compound 1

5K6A の概要

• エントリーDOI: 10.2210/pdb5k6a/pdb
• 分子名称: Pteridine reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (2~{R})-2-(3-hydroxyphenyl)-6-oxidanyl-2,3-dihydrochromen-4-one, ... (6 entities in total)
• 機能のキーワード: trypanosoma brucei, pteridine reductase, oxidoreductase
• 由来する生物種: Trypanosoma brucei brucei; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 126907.87

構造登録者

Landi, G.,Pozzi, C.,Di Pisa, F.,Dello lacono, L.,Mangani, S. (登録日: 2016-05-24, 公開日: 2017-03-22, 最終更新日: 2024-01-10)

• 主引用文献: Di Pisa, F.,Landi, G.,Dello Iacono, L.,Pozzi, C.,Borsari, C.,Ferrari, S.,Santucci, M.,Santarem, N.,Cordeiro-da-Silva, A.,Moraes, C.B.,Alcantara, L.M.,Fontana, V.,Freitas-Junior, L.H.,Gul, S.,Kuzikov, M.,Behrens, B.,Pohner, I.,Wade, R.C.,Costi, M.P.,Mangani, S.; Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity.; Molecules, 22:-, 2017; PubMed: 28282886; DOI: 10.3390/molecules22030426

実験手法

X-RAY DIFFRACTION (1.7 Å)