5JZU

Aspartyl/Asparaginyl beta-hydroxylase (AspH)oxygenase and TPR domains in complex with manganese, N-oxalylglycine and factor X substrate peptide fragment (26mer)

Summary for 5JZU

Entry DOI	10.2210/pdb5jzu/pdb
Descriptor	Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, MANGANESE (II) ION, ... (5 entities in total)
Functional Keywords	2-oxoglutarate dependent oxygenase, aspartyl/asparaginyl beta-hydroxylase, egf-like domain hydroxylase, double stranded beta-helix, tetratricopeptide repeat, oxidoreductase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	52390.33
Authors	McDonough, M.A.,Pfeffer, I. (deposition date: 2016-05-17, release date: 2017-06-07, Last modification date: 2024-01-10)
Primary citation	Pfeffer, I.,Brewitz, L.,Krojer, T.,Jensen, S.A.,Kochan, G.T.,Kershaw, N.J.,Hewitson, K.S.,McNeill, L.A.,Kramer, H.,Munzel, M.,Hopkinson, R.J.,Oppermann, U.,Handford, P.A.,McDonough, M.A.,Schofield, C.J. Aspartate/asparagine-beta-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern. Nat Commun, 10:4910-4910, 2019 Cited by PubMed: 31659163 DOI: 10.1038/s41467-019-12711-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation