5JCU
Crystal Structure of hGSTA1-1 with Glutathione Adduct of Phenethyl Isothiocyanate and Cystein Adduct of Phenethyl Isothiocyanate
Summary for 5JCU
Entry DOI | 10.2210/pdb5jcu/pdb |
Related | 5JCW |
Descriptor | Glutathione S-transferase A1, L-gamma-glutamyl-S-[(2-phenylethyl)carbamothioyl]-L-cysteinylglycine, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | gst, peitc, glutathione adduct, cyctein adduct, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P08263 |
Total number of polymer chains | 4 |
Total formula weight | 105063.32 |
Authors | Kumari, V.,Ji, X. (deposition date: 2016-04-15, release date: 2016-10-12, Last modification date: 2023-09-27) |
Primary citation | Kumari, V.,Dyba, M.A.,Holland, R.J.,Liang, Y.H.,Singh, S.V.,Ji, X. Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical. Plos One, 11:e0163821-e0163821, 2016 Cited by PubMed: 27684484DOI: 10.1371/journal.pone.0163821 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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