5JCJ

Trypanosoma brucei PTR1 in complex with inhibitor NMT-H037 (compound 7)

5JCJ の概要

• エントリーDOI: 10.2210/pdb5jcj/pdb
• 分子名称: Pteridine reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETATE ION, ... (6 entities in total)
• 機能のキーワード: trypanosoma brucei, pteridine reductase, oxydoreductase, inhibitor, oxidoreductase
• 由来する生物種: Trypanosoma brucei brucei; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 126645.58

構造登録者

Landi, G.,Pozzi, C.,Di Pisa, F.,Dello Iacono, L.,Mangani, S. (登録日: 2016-04-15, 公開日: 2016-08-17, 最終更新日: 2024-01-10)

• 主引用文献: Borsari, C.,Luciani, R.,Pozzi, C.,Poehner, I.,Henrich, S.,Trande, M.,Cordeiro-da-Silva, A.,Santarem, N.,Baptista, C.,Tait, A.,Di Pisa, F.,Dello Iacono, L.,Landi, G.,Gul, S.,Wolf, M.,Kuzikov, M.,Ellinger, B.,Reinshagen, J.,Witt, G.,Gribbon, P.,Kohler, M.,Keminer, O.,Behrens, B.,Costantino, L.,Tejera Nevado, P.,Bifeld, E.,Eick, J.,Clos, J.,Torrado, J.,Jimenez-Anton, M.D.,Corral, M.J.,Alunda, J.M.,Pellati, F.,Wade, R.C.,Ferrari, S.,Mangani, S.,Costi, M.P.; Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.; J.Med.Chem., 59:7598-7616, 2016; PubMed: 27411733; DOI: 10.1021/acs.jmedchem.6b00698

実験手法

X-RAY DIFFRACTION (1.76 Å)