5JAQ

Yersinia pestis FabV variant T276C

5JAQ の概要

• エントリーDOI: 10.2210/pdb5jaq/pdb
• 分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, ... (4 entities in total)
• 機能のキーワード: fatty acid biosynthesis fabv, oxidoreductase
• 由来する生物種: Yersinia pestis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45105.71

構造登録者

Pschibul, A.,Kuper, J.,HIrschbeck, M.,Kisker, C. (登録日: 2016-04-12, 公開日: 2016-05-25, 最終更新日: 2024-01-10)

• 主引用文献: Neckles, C.,Pschibul, A.,Lai, C.T.,Hirschbeck, M.,Kuper, J.,Davoodi, S.,Zou, J.,Liu, N.,Pan, P.,Shah, S.,Daryaee, F.,Bommineni, G.R.,Lai, C.,Simmerling, C.,Kisker, C.,Tonge, P.J.; Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase.; Biochemistry, 55:2992-3006, 2016; PubMed: 27136302; DOI: 10.1021/acs.biochem.5b01301

実験手法

X-RAY DIFFRACTION (1.9 Å)