5J80
Crystal Structure of Apo Hsp90-alpha N-domain L107A mutant
Summary for 5J80
Entry DOI | 10.2210/pdb5j80/pdb |
Descriptor | Heat shock protein HSP 90-alpha (2 entities in total) |
Functional Keywords | apo structure, chaperone, l107a |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : P07900 |
Total number of polymer chains | 1 |
Total formula weight | 25285.38 |
Authors | Amaral, M.,Matias, P. (deposition date: 2016-04-07, release date: 2017-12-06, Last modification date: 2024-01-10) |
Primary citation | Amaral, M.,Kokh, D.B.,Bomke, J.,Wegener, A.,Buchstaller, H.P.,Eggenweiler, H.M.,Matias, P.,Sirrenberg, C.,Wade, R.C.,Frech, M. Protein conformational flexibility modulates kinetics and thermodynamics of drug binding. Nat Commun, 8:2276-2276, 2017 Cited by PubMed: 29273709DOI: 10.1038/s41467-017-02258-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.17 Å) |
Structure validation
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