5J1O

Excited state (Bound-like) sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat

5J1O の概要

• エントリーDOI: 10.2210/pdb5j1o/pdb
• NMR情報: BMRB: 30049
• 分子名称: Cyclic peptide mimetic of Tat, Apical region (29mer) of the HIV-1 TAR element (2 entities in total)
• 機能のキーワード: tar:tat complex, ram simulations, residual dipolar couplings, excited state, viral protein
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 11075.74

構造登録者

Borkar, A.N.,Bardaro, M.F.,Varani, G.,Vendruscolo, M. (登録日: 2016-03-29, 公開日: 2016-06-08, 最終更新日: 2019-10-23)

• 主引用文献: Borkar, A.N.,Bardaro, M.F.,Camilloni, C.,Aprile, F.A.,Varani, G.,Vendruscolo, M.; Structure of a low-population binding intermediate in protein-RNA recognition.; Proc.Natl.Acad.Sci.USA, 113:7171-7176, 2016; PubMed: 27286828; DOI: 10.1073/pnas.1521349113

実験手法

SOLUTION NMR