5IZU
A new binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function
Summary for 5IZU
Entry DOI | 10.2210/pdb5izu/pdb |
Descriptor | SH3 and multiple ankyrin repeat domains protein 3, peptide from Disks large-associated protein 3 (3 entities in total) |
Functional Keywords | shank, sapap, pdz, extension, synapse, specific interaction, protein binding |
Biological source | Mus musculus (Mouse) More |
Cellular location | Cytoplasm: Q4ACU6 Cell membrane ; Peripheral membrane protein : Q6PFD5 |
Total number of polymer chains | 4 |
Total formula weight | 34570.93 |
Authors | |
Primary citation | Zeng, M.,Shang, Y.,Guo, T.,He, Q.,Yung, W.H.,Liu, K.,Zhang, M. A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function Proc.Natl.Acad.Sci.USA, 113:E3081-E3090, 2016 Cited by PubMed: 27185935DOI: 10.1073/pnas.1523265113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.494 Å) |
Structure validation
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