5IZU

A new binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function

5IZU の概要

• エントリーDOI: 10.2210/pdb5izu/pdb
• 分子名称: SH3 and multiple ankyrin repeat domains protein 3, peptide from Disks large-associated protein 3 (3 entities in total)
• 機能のキーワード: shank, sapap, pdz, extension, synapse, specific interaction, protein binding
• 由来する生物種: Mus musculus (Mouse); 詳細
• 細胞内の位置: Cytoplasm: Q4ACU6; Cell membrane ; Peripheral membrane protein : Q6PFD5
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 34570.93

構造登録者

Shang, Y.,Zeng, M.,Zhang, M. (登録日: 2016-03-26, 公開日: 2016-05-18, 最終更新日: 2023-11-08)

• 主引用文献: Zeng, M.,Shang, Y.,Guo, T.,He, Q.,Yung, W.H.,Liu, K.,Zhang, M.; A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function; Proc.Natl.Acad.Sci.USA, 113:E3081-E3090, 2016; PubMed: 27185935; DOI: 10.1073/pnas.1523265113

実験手法

X-RAY DIFFRACTION (2.494 Å)