5IZM

The crystal structure of human eEFSec in complex with GDPNP

Summary for 5IZM

Entry DOI	10.2210/pdb5izm/pdb
Related	5IZK 5IZL
Descriptor	Selenocysteine-specific elongation factor, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER (3 entities in total)
Functional Keywords	elongation factor, selenocysteine, selenocysteine trna, translation, gtpase, gdpnp, gtp
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	137876.63
Authors	Dobosz-Bartoszek, M.,Otwinowski, Z.,Simonovic, M. (deposition date: 2016-03-25, release date: 2016-10-12, Last modification date: 2019-11-27)
Primary citation	Dobosz-Bartoszek, M.,Pinkerton, M.H.,Otwinowski, Z.,Chakravarthy, S.,Soll, D.,Copeland, P.R.,Simonovic, M. Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation. Nat Commun, 7:12941-12941, 2016 Cited by PubMed: 27708257 DOI: 10.1038/ncomms12941 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.4 Å)

Structure validation