5IZ8
Protein-protein interaction
Summary for 5IZ8
Entry DOI | 10.2210/pdb5iz8/pdb |
Related | 5IZ6 5IZ9 5IZA |
Descriptor | Adenomatous polyposis coli protein, ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2, TRIETHYLENE GLYCOL, ... (4 entities in total) |
Functional Keywords | apc, asef, colon cancer, drug discovery, protein binding-inhibitor complex, protein binding/inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 80026.07 |
Authors | |
Primary citation | Jiang, H.,Deng, R.,Yang, X.,Shang, J.,Lu, S.,Zhao, Y.,Song, K.,Liu, X.,Zhang, Q.,Chen, Y.,Chinn, Y.E.,Wu, G.,Li, J.,Chen, G.,Yu, J.,Zhang, J. Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat. Chem. Biol., 13:994-1001, 2017 Cited by PubMed: 28759015DOI: 10.1038/nchembio.2442 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.06 Å) |
Structure validation
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