5INO
Human Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex
Summary for 5INO
Entry DOI | 10.2210/pdb5ino/pdb |
Related | 5INK 5INL 5INM 5INN 5INP 5INQ |
Descriptor | Tyrosyl-DNA phosphodiesterase 2, DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), SULFATE ION, ... (4 entities in total) |
Functional Keywords | hydrolase/dna, dna repair, endonuclease/exonuclease/phosphatase (eep) domain, hydrolase-dna complex |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 64191.27 |
Authors | Schellenberg, M.J.,Williams, R.S. (deposition date: 2016-03-07, release date: 2016-04-27, Last modification date: 2023-09-27) |
Primary citation | Schellenberg, M.J.,Perera, L.,Strom, C.N.,Waters, C.A.,Monian, B.,Appel, C.D.,Vilas, C.K.,Williams, J.G.,Ramsden, D.A.,Williams, R.S. Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Res., 44:3829-3844, 2016 Cited by PubMed: 27060144DOI: 10.1093/nar/gkw228 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.205 Å) |
Structure validation
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