5INJ

Crystal Structure of Prenyltransferase PriB Ternary Complex with L-Tryptophan and Dimethylallyl thiolodiphosphate (DMSPP)

5INJ の概要

• エントリーDOI: 10.2210/pdb5inj/pdb
• 分子名称: Prenyltransferase, TRYPTOPHAN, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• 機能のキーワード: prenyltransferase, tryptophan, dmspp, indole-pt, abba family, pt fold, structural genomics, psi-2, protein structure initiative, enzyme discovery for natural product biosynthesis, natpro, transferase
• 由来する生物種: Streptomyces sp. RM-5-8
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43989.22

構造登録者

Cao, H.,Elshahawi, S.,Benach, J.,Wasserman, S.R.,Morisco, L.L.,Koss, J.W.,Thorson, J.S.,Phillips Jr., G.N.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (登録日: 2016-03-07, 公開日: 2016-05-11, 最終更新日: 2024-03-06)

• 主引用文献: Elshahawi, S.I.,Cao, H.,Shaaban, K.A.,Ponomareva, L.V.,Subramanian, T.,Farman, M.L.,Spielmann, H.P.,Phillips, G.N.,Thorson, J.S.,Singh, S.; Structure and specificity of a permissive bacterial C-prenyltransferase.; Nat. Chem. Biol., 13:366-368, 2017; PubMed: 28166207; DOI: 10.1038/nchembio.2285

実験手法

X-RAY DIFFRACTION (1.4 Å)