5IMI
Crystal structure of S303A Aspergillus terreus aristolochene synthase complexed with (1S,8S,9aR)-1,9a-dimethyl-8-(prop-1-en-2-yl)decahydroquinolizin-5-ium
Summary for 5IMI
Entry DOI | 10.2210/pdb5imi/pdb |
Related | 5IMN 5IMP 5IN8 |
Descriptor | Aristolochene synthase, PYROPHOSPHATE 2-, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | lyase, terpene cyclases, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Aspergillus terreus |
Total number of polymer chains | 4 |
Total formula weight | 146742.62 |
Authors | Chen, M.,Christianson, D.W. (deposition date: 2016-03-06, release date: 2016-05-25, Last modification date: 2023-09-27) |
Primary citation | Chen, M.,Chou, W.K.,Al-Lami, N.,Faraldos, J.A.,Allemann, R.K.,Cane, D.E.,Christianson, D.W. Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase. Biochemistry, 55:2864-2874, 2016 Cited by PubMed: 27172425DOI: 10.1021/acs.biochem.6b00343 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.462 Å) |
Structure validation
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