5IM5

Crystal structure of designed two-component self-assembling icosahedral cage I53-40

5IM5 の概要

分子名称Designed Riboflavin synthase, Designed Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase (2 entities in total)
機能のキーワードicosahedron, designed protein cage, two-component, computational design, protein engineering, rosetta, self-assembling, co-assembling, multimerization, symmetry, nanomaterial, nanostructure, protein binding
由来する生物種Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
詳細
ポリマー鎖数30
分子量合計606001.57
構造登録者
Liu, Y.A.,Cascio, D.,Sawaya, M.R.,Bale, J.B.,Collazo, M.J.,Thomas, C.,Sheffler, W.,King, N.P.,Baker, D.,Yeates, T.O. (登録日: 2016-03-05, 公開日: 2016-07-27, 最終更新日: 2016-08-10)
主引用文献
Bale, J.B.,Gonen, S.,Liu, Y.,Sheffler, W.,Ellis, D.,Thomas, C.,Cascio, D.,Yeates, T.O.,Gonen, T.,King, N.P.,Baker, D.
Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353:389-394, 2016
PubMed: 27463675 (主引用文献が同じPDBエントリー)
DOI: 10.1126/science.aaf8818
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (3.699 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2481202.7%0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード