5IJS
Crystal structure of autotaxin with orthovanadate bound as a trigonal bipyramidal intermediate analog
Summary for 5IJS
Entry DOI | 10.2210/pdb5ijs/pdb |
Related | 5dlt 5ijq |
Descriptor | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7alpha-hydroxycholesterol, ... (8 entities in total) |
Functional Keywords | hydrolase, lysophosphatidylcholine, somatomedin, inflammation, metastasis, neuropathic pain, vascular development, neural development |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 1 |
Total formula weight | 96956.95 |
Authors | Hausmann, J.,Joosten, R.P.,Perrakis, A. (deposition date: 2016-03-02, release date: 2016-06-15, Last modification date: 2024-01-10) |
Primary citation | Hausmann, J.,Keune, W.J.,Hipgrave Ederveen, A.L.,van Zeijl, L.,Joosten, R.P.,Perrakis, A. Structural snapshots of the catalytic cycle of the phosphodiesterase Autotaxin. J.Struct.Biol., 195:199-206, 2016 Cited by PubMed: 27268273DOI: 10.1016/j.jsb.2016.06.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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