5IJS

Crystal structure of autotaxin with orthovanadate bound as a trigonal bipyramidal intermediate analog

5IJS の概要

• エントリーDOI: 10.2210/pdb5ijs/pdb
• 関連するPDBエントリー: 5dlt 5ijq
• 分子名称: Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7alpha-hydroxycholesterol, ... (8 entities in total)
• 機能のキーワード: hydrolase, lysophosphatidylcholine, somatomedin, inflammation, metastasis, neuropathic pain, vascular development, neural development
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 96956.95

構造登録者

Hausmann, J.,Joosten, R.P.,Perrakis, A. (登録日: 2016-03-02, 公開日: 2016-06-15, 最終更新日: 2024-01-10)

• 主引用文献: Hausmann, J.,Keune, W.J.,Hipgrave Ederveen, A.L.,van Zeijl, L.,Joosten, R.P.,Perrakis, A.; Structural snapshots of the catalytic cycle of the phosphodiesterase Autotaxin.; J.Struct.Biol., 195:199-206, 2016; PubMed: 27268273; DOI: 10.1016/j.jsb.2016.06.002

実験手法

X-RAY DIFFRACTION (2.2 Å)