5IFB

Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4719 5-chloro-2-(1H-imidazol-1-yl)aniline

5IFB の概要

• エントリーDOI: 10.2210/pdb5ifb/pdb
• 関連するPDBエントリー: 4iuj 5IEQ 5IF2 5IF5 5IF7 5IF8 5ifb
• 分子名称: Polymerase acidic protein, 5-chloro-2-(1H-imidazol-1-yl)aniline, DIMETHYL SULFOXIDE, ... (5 entities in total)
• 機能のキーワード: niaid, structural genomics, flu, fragment screening, std nmr, seattle structural genomics center for infectious disease, ssgcid, viral protein
• 由来する生物種: Influenza A virus (strain A/Wilson-Smith/1933 H1N1)
• 細胞内の位置: Host cytoplasm: P15659
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 53403.94

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2016-02-25, 公開日: 2017-02-22, 最終更新日: 2023-09-27)

• 主引用文献: Pierce, P.,Muruthi, M.M.,Abendroth, J.,Moen, S.O.,Begley, D.W.,Davies, D.R.,Marathias, V.M.,Staker, B.L.,Myler, P.J.,Lorimer, D.D.,Edwards, T.E.; Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA; To Be Published,

実験手法

X-RAY DIFFRACTION (2.45 Å)